Buffalo Bills wide receiver Cole Beasley has a bone to pick with Bills Mafia … calling out the diehard fan base for jeering at him during Sunday’s home game for not getting the COVID-19 vaccine.

“Only place I get boo’d is at our home stadium,” Beasley tweeted Monday. “Then some of the same people want me to take pictures and sign autographs. I thought bills fans were the best in the world? Where’d they go?”

FYI — Highmark Stadium currently requires fans to have at least one shot of the COVID-19 vax in order to attend games.

The 32-year-old wideout has not gotten vaccinated against COVID-19 … and seems to believe that he is being booed by the vaxxed fans at home as a result.

“If the vaccine works then why do vaxxed people need to be protected from unvaxxed? #letemin,” Beasley added.

CB has been openly passionate about his decision to not get vaccinated, saying “I may die of COVID, but I’d rather die actually living.”

A beat reporter for the Bills played devil’s advocate and asked Beasley if the fans were actually chanting “Beaseeeeeeee?” … to which Cole replied, “Some are. Then I got some right behind the bench yelling at me to get vaccinated and talking s***.”

Bills fans have certainly had a lot to cheer about recently … winning 3 straight games after dropping their Week 1 opener to the Pittsburgh Steelers.

It doesn’t seem like this drama is going anywhere anytime soon … that is, unless Beasley decides to get vaccinated.

But, the chances of that happening appear to be VERY slim.

In the meantime, soak in those boo-birds, Bease.